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重组小鼠TNF相关的凋亡诱导配体(TRAIL)
Mouse TRAIL Protein
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活动截止时间:2024年1月31日
重组小鼠TNF相关的凋亡诱导配体(TRAIL)蛋白(Mouse TRAIL Protein)是一种在大肠杆菌中表达的高纯度重组细胞因子,通过先进工艺纯化,纯度 >97%(SDS-PAGE检测),以冻干粉形式提供,适用于细胞培养等研究中凋亡机制的分析与探索。
TRAIL是一种细胞毒性蛋白,能特异性激活肿瘤细胞的快速凋亡,而对正常细胞无显著影响。TRAIL诱导的凋亡过程通过与死亡信号受体DR4和DR5结合实现,这些受体属于TNFR超家族,其胞质"死亡域"可触发凋亡级联反应。重组小鼠TRAIL由全长蛋白胞外域的TNF同源片段(Arg119-Asn291)组成,分子量约20.1 KDa,为细胞因子功能研究提供了可靠工具,广泛应用于肿瘤模型构建和凋亡信号通路分析。
本产品专为细胞类研究设计,核心应用于细胞培养体系中的凋亡诱导实验,支持肿瘤生物学、免疫治疗及细胞信号转导等领域的研究,特别适用于小鼠源模型中的TRAIL功能验证和机制探索。
| 中文名称 | 重组小鼠TNF相关的凋亡诱导配体(TRAIL) |
| 英文名称 | Mouse TRAIL Protein |
| 产品货号 | PRP1302 |
| 序列 | 氨基酸序列来源于:小鼠源TRAIL (P50592) (Arg119-Asn291) 表达的蛋白片段。 |
| 标签 | 无标签 |
| 种属 | 小鼠 |
| 活性 | Testing in Progress |
| 蛋白长度 | 重组小鼠 TRAIL 由173个氨基酸组成,预测分子量为20.1 KD。 |
| 表达宿主 | 大肠杆菌 |
| 纯度 | > 97 % ,使用SDS-PAGE检测 |
| 产品形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 8.0。 |
| 分子量 | 20.1 KDa |
| 基因ID | 284654 |
| 蛋白质ID | P50592 |
| 蛋白序列链接 | https://www.uniprot.org/uniprotkb/P50592 |
| 分子 | TRAIL |
| 检测指标 | TRAIL |
| 注意事项 | 开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于107 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
| 保存建议 | 本产品为冻干粉形式,建议:将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
| 运输条件 | 冰袋运输(蓝冰) |
| 警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
Amino acid sequence derived from Mouse TRAIL (P50592) (Arg119-Asn291) was expressed.
The recombinant Mouse TRAIL consists of 173 amino acids and predicts a molecular mass of 20.1 kDa.
The recombinant Mouse TRAIL consists of 173 amino acids and predicts a molecular mass of 20.1 kDa.
Testing in progress.
Testing in progress.
< 0.1 EU per μg of the protein as determined by the LAL method.
< 0.1 EU per μg of the protein as determined by the LAL method.
Lyophilized from 20mM Tris, 150mM NaCl, pH 8.0.
Lyophilized from 20mM Tris, 150mM NaCl, pH 8.0.
Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Note: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Note: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Disclaimer: This product is for research use only. Not for diagnostic or therapeutic purposes.
Disclaimer: This product is for research use only. Not for diagnostic or therapeutic purposes.
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